Posted by chlorella on Aug 8, 2013 in Chlorella Blog | 0 comments

The evaluation of radioprotective action of a mutant (E-25) form of Chlorella vulgaris in mice was administered at Jawaharlal Nehru University, New Delhi, India, in 1993. The testing studied the possible role of orally fed Chlorella vulgaris (E-25) in radiation-induced mice. “Different doses of E-25 were administered either chronically (once, twice or thrice a day for 28 days) or as single acute doses before/after irradiation. A significant radioprotective effect was observed in both acute and chronic pretreatments, but only at doses above 400 mg/kg body weight.     J. RADIAT. RES., 34, 277-Z84 (1993) Evaluation of Radioprotective Action of a Mutant (E-25) Form of Chlorella vulgaris in Mice LAKSHMI SARMAl , ASHU B. TIKUl , P. C. KESAVAN1* AND M. OGAKIz••Scbool of Life Sciences, Jawaharlal Nehru University, New Delhi-ll0067, India 2Pasteur Institute of Kyoto, 103-5, Tanaka Monzen-Cho, Sakya-ku, Kyoto 606, Japan (Received, May 19, 1993) (Revision received, September14, 1993) (Accepted, September 14, 1993) lScbool of Life Sciences, Jawaharlal Nehru University, New Delhi-ll0067, India 2Pasteur Institute of Kyoto, 103-5, Tanaka Monzen-Cho, Sakya-ku, Kyoto 606, Japan (Received, May 19, 1993) (Revision received, September14, 1993) (Accepted, September 14, 1993) ChlorellD vulgaris E·2S’ Gamma-rays/Radioprotection IMicronuclei, ill vivo The possible role of orally fed ehlere//a vulgaris (E-2S) in modulating the gamma-ray induced chromosomal damage in whole-body irradiated mice was evaluated using a micronucleus test. Different doses of E-2S were administered either chronically (once. twice or thrice a day for 28 days) or as single acute doses before/after irradiation. A significant radioprotective effect was observed in both acute and chronic pretreatments, but only at doses above 400 mg/kg body weight. However, in mice that received E-25 (500 mg/kg) three times a day for 28 days, there was no protective effect, and a significant loss in their body weight was observed. Interestingly, E-2S afforded significant radioprotection even when it was administered within 0.4 hr after irradiation. INTRODUCTION There is growting awareness in the recent years that some of the commonly <:oDsumed food products and beverages contain potential modulators of the effects of environmental mutagenes and carcinogens1,2). Among the diets found to be “protective” in various mammalian systems are the green leafy vegetables, fresh fruits and components of coffee and teaJ –S). More specificially, dietary vitamins, their precursors, trace minerals, chlorophylls, proteins and phenols of plant origin have been shown to reduce the incidence of radiation and chemical carcinogen-induced chromosome breakage in a number of test systems. In the present study, we have tested the radioprotective potential of Chlorella vulgaris E-2S, a freshwater green algae, traditionally used as a nutrition additive, especially as a source of vitamins, specific proteins and assimilated salts. E-25 strain is a mutant form of the heterotrophic type of Chlorella vulgarist isolated by means of • Author for correspondence . L. SARMA ET AL. single cell isolation technique, and cloned by Ogaki and his team in Japan since 1978. The cell-wall of this strain has a very low content of a-cellulose which inhibits its digestibility and absorption in the intestine. In Japan, this algae is produced on a mass-scale by tank cultivation and is available as dry granules under the commercial name “Momotaro E-25”. Experimental and clinical studies over the past two years have indicated that consumption...

Posted by chlorella on Aug 8, 2013 in Chlorella Blog | 0 comments

Chlorella May Help Protect Human Body From Radiation In this informative video, Alex from Vitatalks talks about several substances including Chlorella that may help protect the body from toxic radiation poisoning. Chlorella can help prevent damage to DNA and cellular structure due to its superior antioxidant ability to attack free radicals and assist cells in functioning...